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covid 19: Study finds cancer treatment might inhibit immune therapy to Covid-19 vaccination

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FLORIDA: A new study has found patients with cancer who receive chemotherapy -- and some targeted therapies may mount an inadequate immune response to Covid-19 vaccination. The research has been published in the 'Mayo Clinic Proceedings: Innovation, Quality & Outcomes Journal'. "It is important for patients with cancer who are receiving chemotherapy to receive a Covid-19 vaccine," said Saranya Chumsri, M.D., a Mayo Clinic hematologist and oncologist, and author of the paper. Dr Chumsri said this advice also applied to patients with cancer who are taking a CDK 4/6 inhibitors. These inhibitors are a newer class of medicines used to treat hormone-receptor-positive and HER2-negative breast cancers. Dr Chumsri said that while CDK 4/6 inhibitors are not conventionally considered to be as immunosuppressive as chemotherapy, her research on patients with breast cancer who take these drugs found that they exhibited less optimal neutralizing antibody activity. Dr Chumsri...

rna: RNA-based therapy can protect from many Covid variants: Study

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WASHINGTON: An RNA molecule that stimulates the body's early antiviral defence system may provide protection against a range of SARS-CoV-2 variants, including Delta, according to a study conducted in mice. Ribonucleic acid (RNA) is a single stranded molecule essential in various biological roles and expression of genes. Researchers at Yale School of Medicine in the US noted that the molecule could lead to new treatments for Covid-19 in immunocompromised patients. The research, published recently in the Journal of Experimental Medicine (JEM), could also provide an inexpensive therapeutic option for many developing countries that currently lack access to vaccines. The study was conducted before Omicron was identified and did not test for the variant which is behind the current spike in Covid-19 cases in many countries. The researchers noted that the vaccines against SARS-CoV-2 are highly effective at preventing severe disease and death. However, vaccine availability is extremely ...