My Revolution of PARTs

People who are vaccinated and then get infected with Omicron may be primed to overcome a broad range of coronavirus variants, early research suggests. A pair of studies showed that infection produced even better immune responses than a booster shot in vaccinated patients. Teams from Covid-19 vaccine maker BioNTech SE and the University of Washington posted the results on preprint server bioRxiv in recent weeks. The findings offer a reassuring sign that the millions of vaccinated people who’ve caught Omicron probably won’t become seriously ill from another variant soon -- even though the research needs to be confirmed, especially by real-world evidence. “We should think about breakthrough infections as essentially equivalent to another dose of vaccine,” said John Wherry, a professor and director of the Institute for Immunology at the University of Pennsylvania who wasn’t involved in the research but reviewed the BioNTech study. That could mean that if someone had Covid recently, the...

Why are so many vaccinated people getting Covid-19 lately? A couple of factors are at play, starting with the emergence of the highly contagious Omicron variant. Omicron is more likely to infect people, even if it doesn't make them very sick, and its surge coincided with the holiday travel season in many places. People might mistakenly think the Covid-19 vaccines will completely block infection, but the shots are mainly designed to prevent severe illness, says Louis Mansky, a virus researcher at the University of Minnesota. And the vaccines are still doing their job on that front, particularly for people who've gotten boosters. Two doses of the Pfizer-BioNTech or Moderna vaccines or one dose of the Johnson & Johnson vaccine still offer strong protection against serious illness from omicron. While those initial doses aren't very good at blocking omicron infection, boosters - particularly with the Pfizer and Moderna vaccines - rev up levels of the antibodies to he...